There's definitely funky stuff going on with levels with the QC. It is actually quite tricky to wrap my head around. There's quite a lot of things to account for.
View attachment 29307
XLR outputs are +9.5dBu.
TRS 3+4 outputs are +15.5dBu if you use balanced cables. +9.5dBu if you use unbalanced cables. This is the first source of oddity.
The Send 1+2 outputs are +9.5dBu.
I've connected my Meris MercuryX to the send 1+2 and return 1+2. I've got the Meris setup for true bypass operation currently. I get a level increase when I turn the effects loop block on inside of the Quad Cortex. Which isn't really desirable. I can't say I've had this problem with the Helix or Axe3. I can double check, but I'm pretty sure I can just put a pedal into the loops on those units and get unity gain.
So there seems to be a bit of a juggling act with levels, and tbh, I don't even know where to start with optimizing the signal-path in order to get the right level hitting the front of outboard effects, the right level at the returns of the QC, the right level going into the PA without being too low, and the right level coming out of outputs 3+4 to send to on-stage power amplifiers.
With the Axe3 for instance, I can take a feed from output 3... turn the output 3 level knob on the front all the way up, and I know it is the same level hitting the front of a guitar amp as what it would receive if I just plugged my guitar directly into the amp.
The same does not seem to be the case for the Quad Cortex. I cannot trust that send 1 is the same level as what the amp would see if I was plugged directly in. And debugging this stuff is a mare.
Again to repeat, in 4-cable-method the QC is noticeably noisier than the the Helix and Axe3.
You
can get a good sound. You
can whack a noise-gate after the effects loop block to cut down any extra noise that the QC adds. But you don't need to do that with the other two devices.
It is very odd that the documentation doesn't really point any of this out, and doesn't give you any tools to improve the signal to noise ratio and to ensure unity-gain throughout the system. The Axe3 truly does.
My expectation is that you connect the thing up to a valve amp in 4-cable-method, leave all of the built in trims at 0dB, and there should be no level drops or boosts, and there should be no significant additional noise added.