Well, honestly, while I'm not complaining, I think some sample based items could certainly be optimized.
Take a look at, say, Spectrasonic's Omnisphere 3. The entire library needs 64GB of disk space - and there's some incredibly detailed samples in it, along with >40k patches. Sure, naturally sounding pianos need more space, same goes for strings, horns and what not - but quite some synth sample patches could easily be optimized.
In addition, as said, I really wish I could split the piano libraries - but it's hardly possible as you can only assign one sample location in the plugin.
Sure, I got all that stuff for peanuts, but still. Possibly also explains why the samplebased products seem to be abandoned, most likely just waiting for their EOL.