You know, the only thing the Axe FX can't do that some other devices can is an external control out to switch amp channels without MIDI.
The TC G Major had this, the Headrush devices have this, the Boss GT1000Core has this, the HX Effects has this, I even have a generic $40 DemonFX overdrive that has a separate control out to do this. It's the only feature the Fractal line (other than the old FX8) still seems to be lacking and I'm not sure why. Otherwise they do absolutely everything under the sun.