Thought I'd put this here. Even the image above is out of date now, but roughly the same kind of layout. Except I'm now using the VP4's 4-cable-method as an insert point for all of the other pedals. So signal flow is:
Guitar > Lehle volume pedal > bb535 wah > VP4 > Tumnus > Demhe > Nemesis > DD500 > MercuryX > RV5 > Golden > VP4 Return > Guitar amp input
I run all of my effects up front, because I like it that way. The gain of the amp combined with the spatial effects is very signature to my playing style. But with that many digital pedals in the chain, you do get higher noise floor. So the 4CM puts the effects between slot 3 and 4 on the VP4. This enables slot 4 to be a noise-gate (set to modern expander mode) which really helps to calm down the noise floor of the pedals. You do lose a bit of tail if you're not careful, but all being said... it works rather well.
I'm not sure I'll stick with the setup long-term, but I wanted to try it out at practice last night. It worked really well, but it is a lot of bloomin' pedals!! I might pair it down again. We shall see. I have lots of options now.
I can get a great analog delay from the VP4. The Carbon Copy model is god tier. I can get very satisfying digital delays, and reverse delay is great too. I can get fantastic delay oscillaiton effects too, and the built in EQ on the delay block really helps with that. If I'm honest, I wish the delay block had a better saturation algorithm built into it.
I also can't really get anything satisfyingly glitchy or "fuck shit up" from it - the Helix is honestly much better at that - glitch delay, poly sustain, Euclidean delay, Tesselator, Ratchet.
Helix verbs are not as good as the VP4. But honestly, the VP4 verbs are either not as good - or not as easy to dial in - as the Golden and the RV5 are. Those are such simple pedals. The RV5 is like... just stupidly good. The MercuryX I use it for a big ambient wash, pretty much exclusively... and I'm fairly confident I could get that by using one of the shimmer reverbs on the VP4 if I had to.
Overall, I can't get the VP4 reverbs to be as bright and aggressive as I want. On the full on Axe3 you can obviously have a parallel path, where you can process the reverb with EQ and a bit of grit here and there, maybe I'll try that.
I'm still not against the idea of using the Axe3 for effects. It is a great option. Helix Stadium will hopefully be a great option too when it eventually lands.
The board is actually not that heavy, considering how much it can do. The Helix and Fractal equivalents to a Tumnus are not quite as good as the real pedal IMHO. The Demhe fuzz just shits all over any digital fuzz algorithm as well.