Well, I for one had a hard time to deciper my kitchen sink presets when I was not using them for a longer while.
I'm right now going for a mixed approach with my GT-1000 based setup, I'm using some individual presets for quick and dirty access and some "let's do everything within one preset" creatures as a kinda playground. But obviously that only works because the GT's switching is gapless (including FX trails) and has global blocks (and the external amp sound boxes are "global" as well). It's defenitely not possible to create this kinda setup with a Helix Floor (after all, there's reasons why I sold it, none of them related to sound quality).