I do on occasion but not regularly.
I find them most useful during the initial setup with a given modeler but I may change from the FM9 to the Axe FX III or to my Tone Master Imperial Preamp so I dial in the FR for each.
In addition, on a given day I may feel like everything is too dark or too bright or needs more or less mids.
Particularly in relation to my Fractal gear, it's nice to just be able to grab a knob and make a simple global adjustment.
With that said, I can't remember the last time I made tone adjustments on my FR but I do periodically.