To your other question, if I had a signature amp...it would probably be not far from what Drew described (to a point...).
Sonically, I'd want a three channel amp. BF Bassman clean, Plexi-2203 crunch, and Friedman HBE/EVH 5150 III high gain. Physical knobs to control everything.
Preamp would be all analog designed around the Nutube so you don't have to worry about tube scarcity or quality. Power amp would be high quality class D solid state, either 100 watts per side stereo or bridge to mono, and ability to shut off. Effects loop between the two. Channel switching with MIDI integration. Integrated stereo IR loader with digital room reverb simulation for either DI or through a quality integrated headphone amp. Construction would allow for it to be either a standalone head or easy conversion to rack mounting.
Basically, the idea is to have three really good channels that can cover clean to high gain and be able to integrate with either pedals or any kind of digital effects solution. Flexible enough to run in practically any situation. No expensive tubes to worry about, and no need to crank it and run through an attenuator.
Essentially, it's not far from the Two Notes Revolt or a multi-channel Strymon Iridium, but all analog. You can run it with your Helix, or HX Stomp, or HX Effects, or Axe FX 3, or FM3, or a bunch of pedals, or no pedals.