If you want amp in the room tone, just be sure that there is some room irs corresponding of the cab in the pack you use.
I always mix a little room ir to give some breath.
Example here, in some few minute test of solodallas h30 mix with my fm3, just a little touch of room. I could have use a lot more if I wanted to.
I got that tones from scratch in just few minutes of tweaking, so far from perfect but really enjoyable to play at home.
I just could imagine how easy it must be with an axe III with fullres irs.
Room irs well tweaked are also an alternative for guys like me that does not really like reverbs.