Size: I'd have a rearrange the whole board, to me personally, this outweighs the benefits.
Yeah well, been hassling with that for my first loopswitcher board as well, especially as I always need a case along with it. Turned out to become a custom built thing, which, while ordered as a DIY kit from the local case guru, still was quite expensive. But I kept using that very case for well over 20 years by now (even my latest board incarnation is still using it).
It's also that most typical premade boards won't work well with a loopswitcher as you ideally need two levels, so the cables running out from the back of the loopswitcher could completely run below the actual board level. That's been an easy to solve thing for me, though, I just measured things out and ordered a few ready-cut casewood strips and screwed them together accordingly (cost me 20 bucks or so).
Price: I give you that, €140 is fairly affordable. I've been looking at rather expensive upper-tier ones a few years ago, compared to the Mooer you mentioned, these would've been far outside of my comfort zone (for a mere QOL tool).
To be honest, I would've prefered one of the other contenders (had an eye on the ones from Moen, which are also pretty compact, decently priced and coming with some neat functions) but was rather short on money back then, so I tried the Mooer, which worked a lot better and lived a lot longer than I had expected (had to open it once to clean it and readjust some of the springs between the outer switch and the actual switch on the PCB).
Cables: I currently run a 10-pedal assembly (including a parallel loop blender) using 10 patch cables, all of them EBS Flats. Using 10 pedals in a loop switcher, without stacking, would mean 20 cables.
Defenitely a drawback. But then, once bought, it's done - and it's not that those patch cables would cost a fortune (fwiw, the cheap HB flat ones work as well as the EBS Flats, I have both kinds - and at least in a buffered environment there's no sound difference).
If I was a touring pro and have better gear budget/resources, along with people to transport my stuff, I'd definitely consider going all-in and putting pedals in rack drawers with a huge switching device, e.g. by RJM or such.
I used to use a rack with loopswitcher(s), but ultimately, I love not having to care about a rack and an additional floor controller. Grab pedalboard and that was it - I just love it. Also, once you go for decent rack units, things become expensive quickly.
Fwiw, I wish there were more modeling and FX solutions with analog loops onboard, such as the Tone Master Pro has. Or such as the Boss MS-3, which however has only FX, no modeling, but in case there was a somewhat bigger version (let's say with 6 switches and 1-2 additional loops), I'd defenitely consider it.