Fwiw, back in my HX Floor days, the 2204 Mod used to be my #1 platform for all dirt sounds, but I used it at extremely low gain settings (around 0.8) so I had more variety by using pedals (internal HX ones) in front.
Just fired up HX Native in the Belgian hotel (middle of nowhere) I'm sitting in and still like it, so I just jammed for some minutes. Not necessarily made for that kinda music, though, but if I had nothing else I'd be perfectly happy as well (rhythm is just the amp, lead has the Prize Drive and a bit of Vetta Comp in front).