Reminds me of the Roland VS recorders from 20 years ago. Before every computer could handle multitrack recording they were a good stand alone solution that also had the COSM amps and a bunch of other effects built in. Those units were very practical and professional sounding but also limited. Not just the guitar sounds, but the overall sound (preamps/reverbs/eq/compressors) was fantastic for some bands I recorded, and a struggle for others. Being able to just turn one machine on and be ready to go was really nice though- especially when I was recording on location.
Given my personal workflow, I would disagree. If I was reducing my setup to just a modeler and an interface, I'd have to tab between windows reach for the mouse far too often. I adjust my guitar (and partially mic) volume vs. both my DAW and system sounds almost all the time, so a mixer is of almost paramount value for me
Having all these covered in a convenient package is defenitely something appealing to me.
My Soundcraft Ui24R has 90+% of a Digitech RP1000 built into it. Sucks that's you can't really switch patches though. I mean you could if you built the same snapshot a few times but with a different amp or amp rig in it but that's a PITA because you can't go up and down when switching snaps via footswitch on the mixer. Soundcraft either didn't GAF or didn't think that through. I have used it to add a player at the end of a night for a jam and it does the job in a pinch. Also using the Ui24R with OBS is pretty easy.