I need to do some cable management underneath, but I pretty much have this board completed. The Friedman IR-X is cool by itself, but didn't do it for me with boosts. I am using the GT-1000 Core for effects as well as amp modeling, but bypass the Cab Sims. I run into a Fryette Power Station PS-2A and a Mojotone British 412.
The Morningstar MC8 covers turning off and on effects in the patch like a pedalboard. I am contemplating a second midi cable (Boss midi out to Morningstar midi in) so I can change the options on the Morningstar when I use the down/up switches on the Boss GT-1000 Core.
Patch wise, there will likely be a clean patch, a medium gain patch, a higher gain rock rhythm patch, and a lead patch. My first patch so far uses the Boutique amp, which might be a Dumble or something. It can get pretty high gain with the gain switch (currently set to go from medium to high), overdrive (blues OD which I think is a Bluesbreaker), and solo switch.
Boutique will likely be the light to medium gain patch with the three options above bypassed. I'm thinking the Supreme will cover higher gain stuff, while maybe one of the Fender style amp models cover cleans. I'm not sure what I'll use for the lead patch.
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Edit: I am using a Truetone CS7 power supply to power the Cry Baby Mini, Strobostomp HD tuner, Morningstar MC8, and Boss GT-1000 Core. The EMG ES-918 has batteries (though I hate the way it is implemented, as it making mounting to a pedalboard difficult), and the Mission EP-1 doesn't require power.
Guitar -> EMG ES-918 -> Peterson Strobostomp HD -> Cry Baby Mini -> Boss GT-1000 Core -> Fryette Power Station PS-2A -> Mojotone British 412 cabinet (Celestion Vintage 30/G12H-30 70th Anniversary)