I just hate it with as much of a passion as it gets.
Have been using a SC guitar for a musical once and had to open a tune out of a black (all lights out, so everybody was just intensely listening) with a pretty well distorting sound. Worked fine throughout the rehearsals (sure, some hum, but manageable and easily masked by the actual sound) but that show was in a theatre in the countryside. Soundcheck was still fine, but during the show when all the lights were going, they apparently had the dimmers on the same power circuit as the stage power outlets. So, once Mr. Franck switched on his sound it was like BRRRRRRRRZZZZZZZZZZZZZZRRRRRRRRZZZZZZ, covering around 70% of the guitar volume (seriously, I never ever had it that bad before). Fortunately, the guitar had a reverse wound middle pickup, so I quickly switched to the inbetween position - but we all know how lousy that sounds for rock-ish riffage.
Also, I really love setting up many of my sounds with more gain than what I typically need for rhythm stuff and dial the guitar volume down to clean up. Also only works well with not all that much hum coming from the pickups.
As a result, all of my live guitars are fully humbuck-ed (pseudo single coils included). But I really wish that wasn't necessary.