So I used to use Bareknuckle Pickups pretty religiously. I've had Nailbomb's and Rebel Yell's in my Les Paul over the years. But at a certain point, don't remember when, I started disliking the lack of tightness. So I got some Seymour Duncan Distortions, and that was kind of a gamechanger for me. I love that pickup a LOT.
In my newest Orville By Gibson Les Paul, I currently have an Oil City Pickups Blackbird 'Ulfberht' which was overwound a bit to make it hotter. It is cool, but I will probably replace it with another Duncan Distortion at some point.
To me the DD has the perfect palm mute. I've tried the JB before, and didn't like it as much.
I'm also mildly curious about sticking some Rebel Yell's in my Tokai. But Bareknuckle are sooooooooo expensive now. From £376 for a set. That is just fucking ridiculous. I'm sorry, but that is taking the piss prices. When I bought my Rebel Yell's in 2012, they were £240.
The Duncan Distortion set is £222, which is still quite high if you ask me. But a lot easier to swallow.
I'd also like to try some Tom Anderson pickups, purely based on the fact that Billy Howerdel uses them.