Make a sine wave, measure the voltage in the analog domain with a multimeter. Then feed this sine wave into your input, note down the level in dBFS. You can calculate your headroom with that.
That does make sense.
Turning to 0 doesn't mean extra hiss, unless your signal is extremely quiet and the noise floor of the interface is loud enough to be heard over the other noise in the signal chain. For most interfaces in 2026, you will not have an issue with hiss, nor will you benefit in SNR by turning your interface up by a few dB (as they'll already be hot).
Tried that with my NI Komplete Audio 6, it is a completely different experience between 0 Gain and as much as possible without clipping. Transformers work way better if they're driven hard. It is a bad idea to leave gain at 0.
Audio source was a Guitar with loud Pickups (Fishman Fluence) into High-Z Input.
If you have issues with low signal/high noise, then you'll need to measure your levels and set the gain accordingly. All the info you need is in this forum and on YouTube.
That's basically what I meant with my post. And my complaint was mainly that I'm missing an easy guide to achieve this.
Well, you can turn up your interface's gain knob say by 7 dB and watch for clipping; if there's none, the just subtract 7 dB in the DAW (first thing in the signal chain) and you're good.
Start that way and see on what value (7, 5, 10 dB) you land - first & foremost, avoid clipping the converters.
On many Interfaces there's no reference on how much gain I'm adding. Our digital mixing desk my band is using tells me, the Komplete Audio 6 and the Focusrite you used doesn't.
I assume it is possible by approximating that using your technique. Set to 0, check gain in DAW when strumming the guitar, add gain until shortly before clipping, note down increase and use the same amount to decrease on plugin Input.
FWIW you wouldn't get less hiss by the way with the real amps if you ran that amount of gain.
Only talking from my experience: I had more noise than with real amps on low Input gain settings. Which makes sense, as someone recorded the Amp which adds the gain it always has and afterwards I added noise from low Input gain with bad SNR. There was no perceivable difference when driving the Interface loud.
I wasn't explaining this for the studio-savy folks or audio-engineers and I made that very clear in the opening of the vid - I'm trying to get most folks up & running so that they can make the most of these profiles.
Totally understand that. Still I'm missing a video for tech savvy folks.
Also - again - the best SNR is achieved with high Input gain on the Interface. Try yourself, it will make a huge difference with the Focusrite too.