My first truly great amp was a '67 Bassman bought new in '68. I played it for a long time through a matching Fender cab, and used it on combo organ as well as guitar. A Maestro fuzz and Vox wah rounded out the rig. It was pretty sweet! Whoever mentioned the Bassman is definitely knowledgeable.
For a long time afterward I was mostly a Mesa and then a Two-Rock player, using versions of their Onyx amp. It was their two-channel model, had that Dumble clean and slightly pushed sound, but also could get a bit Marshally when the lead channel was pushed. Great amps, but as with the OP, my tastes changed a little after about a decade. I don't know why, but I wanted to get back to more basic tones.
In the last 12 years I've put together this rig; it's kind of a mishmash of different sounds as taste and needs have evolved, but WTF, they're all sounds I like!

I'm not a high gain player, but can head in that direction if that's what a client wants (though I just usually hire a high gain player and try to do it the right way!).
1. PRS HXDA. It's an actual clone of Duane Allman's 'Live at the Fillmore' Superbass, switchable to a Superlead - as someone mentioned above about the Superbass and Superlead similarity in parts allowing one to be converted to the other, PRS' amp guru decided since the parts weren't all that different, why not make them switchable?
So it switches progressively from 'DA', the Superbass, to 'HX', the Superlead. It sounds very authentic. I have it loaded with NOS Mullard preamp tubes, and NOS Siemens EL34s. When it's set to 'DA" with the right guitar, you can hear right away it's that 'Live at the Fillmore' tone. Made the hairs on the back of my neck stand up the first time I played through it. Has a nice sounding master volume as well.
They borrowed Duane's amp from its owner who apparently worked for the band for a long time; The Allman Brothers were PRS amp endorsers until Gregg Allman's death, when the band more or less dissolved, so they were able to get their hands on the amp easily. It's a very interesting amp!
Doug Sewell, the amp's designer suggested trying the Siemens NOS tubes if I wanted to come as close as possible to the NOS Mullard tones without spending a fortune. I got some, it was good advice.
2. PRS DG30. David Grissom worked with PRS on this amp. He wanted a combination of the tones of his Tweed amps, his Hiwatt and Vox. So it has the tone stack of a Hiwatt, 4xEL84Ms in the power section (a higher-plate voltage variant of the EL84) similar to a Vox, a GZ34 rectifier, and this one came from the factory with NOS Brimar 12AX7s. The power tubes are NOS Russian military. They did this for the first 20 made. The amp sounds like nothing else I've ever played through. It's a single channel amp, and it sounds different depending on how you set it up. I think it's a phenomenal amp. I generally run it old school, with the Master Volume nearly full up, using the gain control and guitar controls for volume, but the Master actually sounds quite good and is useful when needed (which, if you're sane, is often - sometimes I'm sane, sometimes not).
3. Mark VII. You all know this amp, I got mine a couple of months ago and love it. The thing blows me away every time I use it. I think this one would be a desert island choice. The tones it can produce are (IMHO) spectacular.
4. Mesa Fillmore. This is a Tweed based amp, I'm sure everyone here is familiar with it. The clean and gain tones are wonderful, and different from the Mark and the Lone Star. I installed a set of NOS GE preamp tubes that I think improve the amp's warmth and give it a slightly more vintage vibe. It's subtle, but the change made me love the amp more.
5. Mesa Lone Star. This is really based on a Black Panel Fender, but with more of a Mesa-style midrange, and more or less goes in Mesa's direction from there. I wasn't certain I'd keep it until I loaded it with NOS RCA and GE preamp tubes. I also installed NOS Siemens EL34s just on a whim (it's got a switch to do that) and liked the lead channel of the amp a lot more. Thus it gives me different tones from the Mark VII though I can get extremely close to its clean tone with the Mark. The lead channel is quite different.
I compose and produce ad music using these amps, and sometimes deadlines get a little nuts and there isn't much time to swap cables around and try different cabs, so I got a Swiss KHE amp switcher. It doesn't suck tone, it's transparent, switching is by noiseless relays. It can handle 8 amps and 4 cabs. The switching is instantaneous, so I when I dial in a sound, I can try each amp with every cab at the flick of a switch, which is actually pretty convenient in the heat of a session (especially with clients breathing down my neck). I generally set up a mic on each cab during production sessions so I'm ready to roll without wasting any time.
I've got some pedals that are self-explanatory.
This is my setup, it's all in one fairly long shoebox-shaped room. There's nothing particularly special about the room - it's a typical basement space that I hung acoustic treatment in, but it sounds very good in both areas, and I've done a lot of ad work here (as well as my own stuff). I call it Studio Craptastic for obvious reasons.
Recording area with amps, etc.
Workstation